Semler Scientific’s Ambitious Bitcoin Treasury Strategy
California-based med tech firm Semler Scientific has announced its plans to significantly expand its Bitcoin holdings over the next few years. The company aims to hold 10,000 BTC by the end of 2025, 42,000 BTC by the end of 2026, and a whopping 105,000 BTC by 2027.
These purchases will be funded through a combination of equity and debt financing, as well as operational cash flow. Semler has also appointed Joe Burnett as director of Bitcoin strategy to oversee the treasury expansion.
Burnett, a seasoned Bitcoin advocate, will lead the company in establishing one of the largest corporate Bitcoin treasuries globally. Semler’s decision to focus on Bitcoin as a long-term asset aligns with its belief in the cryptocurrency’s potential as the ultimate store of value.
Since adopting Bitcoin as its primary treasury reserve asset in May 2024, Semler has seen significant returns. As of June 3, the company has achieved a 287% Bitcoin yield and $177 million in unrealized gains on its BTC holdings.
Semler’s Bitcoin Acquisition
Recent filings reveal Semler’s aggressive approach to accumulating Bitcoin. In the first quarter of 2025, the company acquired 894 BTC at a cost of $90.7 million. Subsequent purchases in April and May brought the total holdings to 3,808 BTC, with a cost basis of $340 million and a fair value of $387.9 million.
Despite operating losses in its healthcare business, Semler’s Bitcoin strategy has proven fruitful. The company reported a 22.2% BTC yield in the first quarter of 2025 and continues to see positive returns on its holdings.
Industry Trends
Semler’s approach to Bitcoin mirrors a broader trend among publicly traded companies worldwide. Tokyo-listed Metaplanet, for example, surpassed 10,000 BTC in holdings ahead of schedule and has set even more ambitious targets for the coming years.
Metaplanet aims to hold 100,000 BTC by the end of 2026 and 210,000 BTC by 2027, representing 1% of Bitcoin’s total supply. These companies’ strategic focus on Bitcoin highlights the increasing adoption of cryptocurrencies as a key asset class in corporate treasuries.

